What is LCA?

Leber’s Congenital Amaurosis (LCA) is a very rare, genetic hereditary disorder that causes severe vision loss and blindness in infants and children. Of all the retinal degenerations, LCA has the earliest age of onset and can be the most severe. LCA is an autosomal recessive disease, which means both parents are carriers of the disease. There are approximately 3,000 people in the U.S. with LCA.

There are approximately 15 known genes that have been identified to cause LCA. Further explanation of LCA and in depth explanation of genes can be found on the Foundation for Retinal Research website. http://www.tfrr.org/index.php?m=19#7

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